The significant overlap between tumor prosurvival and proliferative genes activated by STAT3 and NF-κβ, is not surprising based on data showing that STAT3 maintains the acetylation and nuclear retention of the NF-ΚΒ transcriptional subunit RelA in Du145 PCa cells as well as hematopoietic cells [45]. The gene discussed is STAT3; the disease is posterior cortical atrophy.