At 12 weeks post-infection with AJEJJenv, the Akt2−/− mice had a substantial and statistically significant greater number of small and medium sized lung tumors as compared to Akt3−/− mice, which had only a few detectable tumors, and WT and Akt1−/− mice, which had no detectable tumors (Figure 3A). This evidence concerns the gene AKT3 and infection.