Indeed, the mean serum TFF3 concentration in patients with gastric cancer was 50.95 ± 2.31 ng/ml (95% CI [46.35, 55.55]), while in CAG, CNAG and healthy groups it was 31.41 ± 1.34 ng/ml (95% CI [28.74, 34.09], P < 0.0001), 32.30 ± 2.09 ng/ml (95% CI [28.00, 36.59], P < 0.0001) and 30.67 ± 2.20 ng/ml (95% CI [26.22, 35.13], P < 0.0001), respectively. This evidence concerns the gene TFF3 and gastric cancer.