As shown in Figure 2(a), HER2 protein expression was not changed in response to treatments with DMSO or proteasomal inhibitors in both parental (Hep3B and HepG2) and HBx-expressing HCC (Hep3Bx and HepG2x) cells, indicating that HBx does not regulate HER2 expression at posttranslational level. Here, ERBB2 is linked to hepatocellular carcinoma.