Initial studies identified T2D-associated variants in loci harboring genes such as CDK5 regulatory subunit associated protein 1-like 1 (CDKAL1), solute carrier family 30 (zinc transporter), member 8 (SLC30A8), homeobox hematopoietically expressed (HHEX), insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2), and cyclin-dependent kinase inhibitor 2A/2B (CDKN2A/2B) [17–19, 23, 26]. Here, CDKAL1 is linked to type 2 diabetes mellitus.