Statistical analysis (Mann–Whitney two-tailed test) indicated that the relative quantity (R.Q.)of HGF mRNA in MM biopsies (mean ± SD = 39.1 ± 69.1; range = 1.0 – 288.7) was significantly higher than that measured in healthy individuals (mean = 5.0 ± 2.4; range = 2.0 – 9.8) (p < 0.0001). This evidence concerns the gene HGF and Miyoshi myopathy.