For this reason, we investigated the DNA methylation status of MUC1, MUC2 and MUC4 in 45 samples of pancreatic juice collected from patients with PDAC, intestinal-type IPMN, gastric-type IPMN, other-type IPMN and non-neoplastic pancreas. The gene discussed is MUC1; the disease is pancreatic intraductal papillary-mucinous neoplasm.