MUC1 and familial pancreatic carcinoma: In analyses of pancreatic neoplastic and non-neoplastic tissues of PDAC samples in this study, we found a strong relationship between the mRNA expression level and DNA methylation status for MUC1. This is similar to the results in pancreatic cancer cell lines in our previous study [14] and suggests that DNA methylation has a key role in MUC1 regulation in human pancreatic tissue.