Childhood phacomatoses such as Sturge Weber, Klippel-Trenaunay-Weber Syndrome, Wyburn-Mason syndrome, tuberous sclerosis, and neurofibromatosis I, as well as Aicardi Syndrome, the Ring 14 Syndrome [18], and CASK mutation [19] all present with epilepsy in childhood and have different mechanisms of elevating IOP (Table 2). Here, CASK is linked to Wyburn-Mason syndrome.