This study observed that the levels of WBC, HGB, ALT, BUN, Scr, glucose, PT, APTT and TT in the critical patients were higher or longer than the reference value, while the levels of PLT and ALB were lower than the reference value (Table 6), which indicated that critical patients with HFRS usually had obvious hepatic and kidney injury, and stress hyperglycemia and hypermetabolism were also common during the clinical course. Here, GPT is linked to Hyperglycemia.