With regard to AR, after heating sections by autoclaving in Diva Decloaker (Biocare Medical) independent of the pH of the AR solution for 5 min (heating-AR independent of pH, Table 1), there were no cleaved caspase-3+ cells evident (Figure 4c) whereas lymphoma cells expressed scant expression of Bcl-2 (Figure 4d), moderate expression of Flip (Figure 4e) and strong expression of survivin (Figure 4f) [15], suggesting that neoplastic expression of survivin suppresses cleaved caspase-3. The gene discussed is BIRC5; the disease is lymphoma.