Interestingly, the SWIP response in hlh-17(ns204) animals is enhanced by pre-treatment with bupropion, an antidepressant and DAT inhibitor that is used to treat ADHD in adults and children (Faraone and Glatt 2010; Jafarinia et al. 2012) but is unaffected by the antidepressant fluoxetine and the dopamine antagonist, reserpine. The gene discussed is WASHC4; the disease is attention deficit-hyperactivity disorder.