TRPS1 has begun to attract wide attention as an important regulator of apoptosis, as it has been found that TRPS1 protein expression is androgen-suppressive in androgen-dependent (LNCaP-FGC) prostate cancer cells but not in androgen-independent (LNCaP-LNO) prostate cancer cells [47]. This evidence concerns the gene TRPS1 and Familial prostate cancer.