Furthermore, the tumor cells exhibited positive immunohistochemical staining for vimentin, CD21, CD35, D2-40 and leukocyte common antigen (Figure 3A to 3E) as well as negative staining for cytokeratin (Figure 3F), CD20, CD30, CD117, epithelial membrane antigen and S-l00 (not shown). The gene discussed is PDPN; the disease is neoplasm.