The analysis revealed distinct significant aberrancies in the level of four ligands: JAG1, JAG2, DLL1, and DLL4. We observed an over-expression of JAG1 and DLL1 (Figure 1b and d, respectively) and a down-regulation of JAG2 and DLL4 (Figure 1c and f, respectively), whereas DLL3 expression in MB tumor samples was comparable to that in cerebellum controls (Figure 1e). The gene discussed is JAG2; the disease is neoplasm.