DLL4 and neoplasm: The analysis revealed distinct significant aberrancies in the level of four ligands: JAG1, JAG2, DLL1, and DLL4. We observed an over-expression of JAG1 and DLL1 (Figure 1b and d, respectively) and a down-regulation of JAG2 and DLL4 (Figure 1c and f, respectively), whereas DLL3 expression in MB tumor samples was comparable to that in cerebellum controls (Figure 1e).