SOD1 and amyotrophic lateral sclerosis: Golgi fragmentation is a well-established feature of ALS spinal and cortical motor neurons, that also occurs in some other neurodegenerative conditions, is reproduced in SOD1-ALS mice and some cellular ALS models [6,60], but is not found in degenerating motor neuron in a non-ALS disorder [61] and non-ALS mouse models [62].