Based on the predictions of putative target genes and pathways determined using miRFocus (Table 6), we have found that these miRNAs are potentially involved in several important biological processes and functional pathways associated with AF (e.g., TGF-beta, MAPK, VEGF, Calcium, Gap junction, mTOR, and Wnt signalling pathway, most of which have been implicated in the pathogenesis of AF). This evidence concerns the gene MTOR and atrial fibrillation.