To investigate whether CD44 expression patterns are related to pancreatic carcinoma metastasis and prognosis, we designed a primer specific for each CD44 variant (CD44v2-CD44v10 and CD44s), detected the expression patterns of CD44 in 101 clinical pancreatic carcinoma samples, and analyzed the relationship of those patterns with the clinical characteristics of pancreatic carcinoma. The gene discussed is CD44; the disease is exocrine pancreatic carcinoma.