Taking into account our findings and the need to identify new valuable prognostic factors for baseline resistance, we suggest that if our results are confirmed on a larger study, the assessment of nuclear expression of FANCD2, RAD51, BRCA1 and BRIP1 proteins could represent a supplementary prognostic factor that would better tailor the treatment for patients with advanced cervical cancer. The gene discussed is BRIP1; the disease is cervical cancer.