iPer a 5 and bPer a 5 at 1.0 μg/mL induced approximately up to 4.5- and 3.2-fold increase in the expression of CD63 and CCR3 in CD63 and CCR3 double positive cells when incubating with passively sensitized basophils (by sera from American CR allergy). This evidence concerns the gene CCR3 and allergic disease.