iPer a 5 and bPer a 5 at 1.0 μg/mL induced approximately up to 4.5- and 3.2-fold increase in the expression of CD63 and CCR3 in CD63 and CCR3 double positive cells when incubating with passively sensitized basophils (by sera from American CR allergy). The gene discussed is CD63; the disease is Allergy.