More recently, a comprehensive microarray study of DN kidney biopsies from ethnically diverse patients microdissected into glomerular and tubulointerstitial compartments identified both common and distinct expression networks and pathways implicated in disease, including the complement cascade, RhoA, Cdc42, integrin, integrin-linked kinase, and vascular endothelial growth factor signaling in DN glomeruli [82]. The gene discussed is CDC42; the disease is liver dysplastic nodule.