CLN3 and obesity due to melanocortin 4 receptor deficiency: CLN3 maps to chromosome 16p11.2 distal to regions previously associated with developmental delay, autism and obesity (Weiss et al., 2008; Bachmann-Gagescu et al., 2010; Bochukova et al., 2010; Rosenfeld et al., 2010; Walters et al., 2010).