The primary endpoint of improved combined global left and right ventricular ejection fraction as assessed by magnetic resonance imaging was not met, and while there was a trend towards reduced major adverse cardiac events this was not significant (“Safety and efficacy of SITAgliptin plus Granulocyte-colony stimulating factor in patients suffering from Acute Myocardial Infarction — SITAGRAMI trial”). This evidence concerns the gene CSF3 and acute myocardial infarction.