It was reported that integrins mediated CAM-DR by upregulation of antiapoptotic Bcl-2.19 To gain insight into the mechanism of MGr1-Ag in CAM-DR, we first examined the adhesive potential of three GC cell lines, including two MDR GC cell lines SGC7901/VCR and SGC7901/adriamycin (ADR), as well as drug-sensitive cell line SGC7901, to LN. Here, BCL2 is linked to gastric cancer.