NOS has been identified in cochlear nucleus (CN) neurons (Fessenden et al., 1999; Burette et al., 2001; Zheng et al., 2006) an area where profound changes, believed to contribute to tinnitus generation, have previously been demonstrated (Kaltenbach & Afman, 2000; Kraus et al., 2011; Vogler et al., 2011). Here, NOS1 is linked to Tinnitus.