SGCB and Hepatic fibrosis: Of note, the sGC activator BAY 60-2770 inhibited myofibroblast differentiation in prostatic and dermal fibroblasts (our unpublished observations) and attenuated liver fibrosis in rat models [110], whilst the sGC activator cinaciguat (BAY 58-2667) prevented disease progression in a rat model of chronic renal failure [111].