TGFB1 and neoplasm: We investigated thyroid hormones levels in menopausal BrC patients because of their lack of estrogen and verified the action of T3 on genes regulated by E2 (TGFA, TGFB1, and PGR) [7] and T3 (TNFRSF9, BMP6, and THRA) [29] in primary BrC tissues exhibiting the early stages of tumor progression.