KLK3 and Familial prostate cancer: We did not find that other prostate cancer specific prognostic factors were differential between those who died and those alive at last followup including PSA doubling time (20.3 versus 32.9 months; P = 0.55), interval to PSA failure (47.2 versus 57.4 months; P = 0.44), and most recent PSA level (2.4 versus 4.7 ng/mL; P = 0.16).