DERL3 and cancer: Using the aforementioned microarray platform in a large set of human cancer cell lines (n=346) from 14 tumour types, we observed that DERL3 promoter CpG island methylation was commonly found in solid tumours, such as head and neck, breast, liver, oesophageal, prostate and lung carcinomas (Fig. 6e and Supplementary Table 3), but not in leukaemia.