SELE and small cell lung carcinoma: Using a in vitro flow assay, Richter et al. could show that E-selectin binding in this assay correlated well with the metastatic behavior of the SCLC cells in pfp/rag2 mice, i.e. cell lines with a higher number of adhesive events also showed a higher number of spontaneous lung metastases than those with lower number of adhesive events [20].