Although IL-19 has been shown to be increased in both Th1- and Th2-dominant diseases such as psoriasis and asthma, respectively [15], [16], data from IL-19 deficient mice and human data autoimmune diseases and other inflammatory conditions suggest that IL-19 has a potent anti-inflammatory activity [26], [27], [28]. The gene discussed is IL19; the disease is autoimmune disease.