CBFB and acute myeloid leukemia: In mutated group, cytogenetic and molecular studies revealed that 4 cases (22.2%) are associated with AML specific abnormalities, namely, PML-RARA/t (15; 17)(q22; q21), AML-ETO t(8; 21)(q22; q22), CBFB/inv(16)(p13; q22), and MLL (DC,BAR)/11q23.