This study which is considered the first study done in Saudi Arabia focuses on frequency and prognosis of the presence of FLT3 mutations in adult and pediatric acute myeloid leukemia patients; only one study was done for detection of FLT3 oncogene mutations in adult acute myeloid leukemia using conformation sensitive gel electrophoresis [11]. This evidence concerns the gene FLT3 and acute myeloid leukemia.