In addition, among the biological functions related to these proteins, 15 differentially expressed proteins (DEFA1, S100A9, LCN2, S100A8, IGHM, HIST1H2BK, IGJ, PRDX2, ACTB, FGA, CD14, HP, FCGR3A, TIMP1, APOE), classified in infectious disease, were significantly associated with viral infection (p-value: 2.58E-05). Here, DEFA1 is linked to infectious disease.