In addition, among the biological functions related to these proteins, 15 differentially expressed proteins (DEFA1, S100A9, LCN2, S100A8, IGHM, HIST1H2BK, IGJ, PRDX2, ACTB, FGA, CD14, HP, FCGR3A, TIMP1, APOE), classified in infectious disease, were significantly associated with viral infection (p-value: 2.58E-05). This evidence concerns the gene TIMP1 and viral infectious disease.