In the present study we will examine factors related to donor (age, liver steatosis), pre-transplant recipient (age, sex, HCV viral load, coinfections, SNPs of OAS gene, IL1β and IL-28β gene and posttransplant recipient immunosuppressive drugs, i.e., cyclosporine (CS), FK, and mycophenolate mofetil (MMF)), and their association with HCV recurrence following liver transplantation. The gene discussed is IL1B; the disease is fatty liver disease.