MAPK3 and infection: We observed that, Mycobacterium tuberculosis H37Rv infection was associated with significantly augmented histone phosphorylation and acetylation at the IL-10 locus (Figure 2I and 2J) whereas CCR5 silencing or inhibition of Lyn or ERK1/2 resulted in drastic reduction of both histone phosphorylation and acetylation at the same locus.