Genes involved in CRC, such as MYC (v-myc avian myelocytomatosis viral oncogene homolog) [40]CCNB1 (cyclin B1) [41] and PLK1 (polo-like kinase 1) [42], were up-regulated and concordantly amplified in copy number in our study. Here, PLK1 is linked to colorectal carcinoma.