Specifically CTL, NKT, γδT, NK, and IFNγ (Th1 type) cells were up-regulated, and Th17, PMN-MDSC, IL-6 and IL-8 (Th2 type) immune cells were inhibited [14], suggesting embelin can inhibit pancreatic cancer growth and inflammation by modulating tumor immune microenvironment. This evidence concerns the gene CXCL8 and familial pancreatic carcinoma.