Of note, although the independent prognostic value of PIGR expression was retained when adjusting for tumour location in the multivariable model, stratified analysis according to location revealed that the prognostic value of PIGR was largely attributed to tumours located to the esophagus and GEJ, and that PIGR expression was not an independent prognostic factor in separate analysis by tumour location. Here, PIGR is linked to neoplasm.