As shown in Figure 4B, the PBMCs in the presence of both trastuzumab and the inactivated cancer cells (trastuzumab-coated cancer cells) had significantly higher IFN-γ mRNA than that in the other three conditions: PBMCs only, PBMCs with trastuzumab alone, or PBMCs with the inactivated cancer cell alone (Figure 4B). Here, IFNG is linked to cancer.