Among patients with anaemia, there was a higher percentage of TLR7-positive CD3+  (4.19% ± 5.45), CD4+  (4.19% ± 5.45), and CD19+ cells (5.87% ± 8.71), compared to patients with haemoglobin concentration >12 g/dL (0.55% ± 1.08, P < 0.05; 0.55% ± 1.08, P < 0.03; 0.85% ± 2.24, P < 0.02, resp). The gene discussed is CD4; the disease is anemia.