Significantly higher percentages of TLR3- and TLR9-positive PBMCs and CD3+ T lymphocytes, including those positive for CD4 and CD8 antigens, as well as CD19+ B lymphocytes were observed among patients with SLE, compared to healthy controls (Figures 2 and 3). The gene discussed is TLR9; the disease is systemic lupus erythematosus.