In this regard, chemokines like CCL2/MCP-1, CCL5/RANTES, macrophage inflammatory protein-2 (CXCL2/MIP-2), and γ-interferon-inducible protein (CXCL10/IP-10) have been evaluated in experimental hydronephrosis [49–53]. The gene discussed is CXCL10; the disease is hydronephrosis.