Interestingly, opioids can induce phosphorylation of the EGFR; hence, the growth of cancer cells expressing EGFR and MOR at different rates in the so-called postoperative minimal residual disease (MRD; circulating tumor cells, micrometastasis, and positive surgical margins) could be modulated differently by the different opioids 27. The gene discussed is EGFR; the disease is neoplasm.