Yusuf et al. [1], using data from the INTERHEART study, which involved individuals from 52 high, middle, and low income countries and included 6,086 Chinese, suggested that smoking and elevated apolipoproteins (ApoB/ApoA1 ratio) were the most important risk factors for myocardial infarction across geographic regions and in both sexes, and abdominal obesity, as well as other factors such as psychosocial characteristics, diabetes, and hypertension, were the next most important risk factors in men and women. The gene discussed is APOA1; the disease is myocardial infarction.