NFKB1 and Alzheimer disease: Although one individual with AD (Subject 2) displayed weak interaction of TDP-43 with p65 NF-κB by immunoprecipitation assays, this subject displayed low concentration of TDP-43 and p65 (Figure 1a, Additional file 2: Table S1) and low frequencies of colocalization of TDP-43 with p65 (Figure 3c).