They found that the primary tumor of C3H mice injected with cadherin-transfected LM8 cells contained higher levels of cadherins compared with those injected with control, empty vector-transfected LM8 cells and that a high number of metastatic lesions were present in the lung of the latter mice, whereas there was a marked reduction in pulmonary metastases in the former mice. Here, CDH17 is linked to neoplasm.