SMAD3 and Parkinson disease: CTNNB1 (catenin, beta 1) has the record environment of ten (!)nearest neighbors in the compacted shortest path network (CSPNW, Figure 5) all of which known to be involved in Parkinson's disease (AKT1, CASP3, CASP6, CDK5, CREB1, MAPK8, NR4A2, PTEN, RAC1 and SMAD3).