CTNNB1 (catenin, beta 1) has the record environment of ten (!)nearest neighbors in the compacted shortest path network (CSPNW, Figure 5) all of which known to be involved in Parkinson's disease (AKT1, CASP3, CASP6, CDK5, CREB1, MAPK8, NR4A2, PTEN, RAC1 and SMAD3). The gene discussed is AKT1; the disease is Parkinson disease.