CTNNB1 (catenin, beta 1) has the record environment of ten (!)nearest neighbors in the compacted shortest path network (CSPNW, Figure 5) all of which known to be involved in Parkinson's disease (AKT1, CASP3, CASP6, CDK5, CREB1, MAPK8, NR4A2, PTEN, RAC1 and SMAD3). The gene discussed is MAPK8; the disease is Parkinson disease.