Gene signatures such as IL6, MMP9, MMP1, IFNGR1, CXCL12, FOSB, LCK, CCL21, DARC, ERG, MYH11,RHOJ, IGF1, ETS1 which have been identified in our research are present both in cancer pathways and beta-adrenergic pathways. This evidence concerns the gene MMP1 and cancer.