INS and Insulin resistance: None of the investigated traits, i.e. 2 h glucose (OGTT), Hb1Ac, fasting glucose, fasting insulin, insulin resistance (HOMA-IR), β-cell activity (HOMA-B), total/HDL/LDL cholesterol, triglycerides and type 2 diabetes (26–32), demonstrated evidence for association (all P > 0.05) with rs2149954 (Supplementary Material, Tables S8 and S9).