TNFRSF1A and aneurysm: Because IA formation in the mouse model was greatly influenced by systemic blood pressure, we confirmed the independence of genotypes from systemic blood pressure after aneurysm induction (systolic blood pressure: wild-type mice, 115.0 ± 10.3 mmHg, n = 8; TNFR1-heterozygous mice, 113.0 ± 9.0 mmHg, n = 7; TNFR1-deficient mice, 112.3 ± 8.6 mmHg, n = 8; mean blood pressure: wild-type mice, 77.3 ± 7.2 mmHg, n = 8; TNFR1-heterozygous mice, 78.1 ± 9.8 mmHg, n = 7; TNFR1-deficient mice, 74.8 ± 3.9 mmHg, n = 8) (Figure 2B).