We next studied the expression of TMEM106B in the frontal cortex and the hippocampus of six AD cases and 13 non-AD cases, composed of four NC cases, four ALS cases, three PD cases, and two MSA cases, presented in Table 1, by immunohistochemistry using the A303-439A antibody. This evidence concerns the gene TMEM106B and amyotrophic lateral sclerosis.