By reverse transcriptase-PCR, all cells and tissues examined – including the human cerebrum, astrocytes, neuronal progenitor cells, NTera2 teratocarcinoma-derived neurons, SK-N-SH neuroblastoma, IMR-32 neuroblastoma, U-373MG glioblastoma, T98 glioblastoma, and HMO6 immortalized microglia – expressed varying levels of TMEM106A, TMEM106B, TMEM106C, and PGRN transcripts (Figure 2a,b,c,d, lanes 1,3 to 10). The gene discussed is GRN; the disease is neuroblastoma.