Consequently, the NRG1 genotype-dependent perihippocampal FA changes found in our study could be an anatomical marker for increased vulnerability, in particular when considering findings on the Dysbindin (DTNBP1) rs1018381 schizophrenia susceptibility variant, which was associated with FA reductions in the right perihippocampal region (Nickl-Jockschat et al. 2012). Here, NRG1 is linked to schizophrenia.